The 2025 European Society of Urogenital Radiology (ESUR) consensus updates the society's earlier guidance on pelvic MRI for endometriosis. Its central message is practical: a technically adequate examination, standardized terminology, and systematic compartment-based mapping are all necessary if MRI is to support multidisciplinary decision-making and surgical planning.
The update provides a practical framework for MRI protocol design, standardized terminology, compartment-based analysis, and structured reporting.
Clinical scope This article is an educational summary for radiology professionals. It does not replace the full consensus documents, local protocols, multidisciplinary discussion, or patient-specific clinical judgment.
Why this consensus matters
The consensus addresses four recurring sources of variation in endometriosis MRI:
- Patient preparation and acquisition technique
- Terminology used to describe disease
- Anatomic mapping of deep endometriosis
- Measurements and descriptors needed by gynecologists and surgeons
The most consequential reporting change is the recommendation to evaluate deep endometriosis using a compartment-based map, rather than describing lesions as an unstructured list. This creates a repeatable search pattern and helps the radiologist communicate disease extent in surgically relevant terms.
MRI protocol
Patient preparation
| Preparation item | ESUR recommendation | Practical note |
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| Menstrual-cycle timing | No specific timing is required | Do not delay an otherwise indicated examination solely to match a cycle phase. |
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| Fasting | Recommended | Follow local safety and medication policies. |
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| Antiperistaltic agent | Recommended | When used, administer close to the most informative T2-weighted acquisitions. |
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| Bladder filling | Moderate filling is highly recommended | The consensus suggests voiding 30–60 minutes before the examination after drinking water. |
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| Bowel preparation | Highly recommended | Options vary by institution and may include an enema, suppository, evacuation, laxative, or low-residue regimen. |
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| Vaginal opacification | Optional | May be useful in selected cases; it is not recommended as a routine requirement. |
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| Rectal opacification | Optional | Use selectively because luminal material may obscure adjacent lesions. |
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| Patient position | Supine | Phased-array coils are recommended at both 1.5 T and 3 T. |
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Essential sequences
A core examination should include:
- Sagittal T2-weighted imaging
- Axial T2-weighted imaging
- T1-weighted imaging with and without fat suppression, or a Dixon technique
- A sequence that includes the kidneys
The kidney-containing sequence is important because ureteric disease can cause upstream dilatation that may be missed on a pelvis-only field of view.
Optional or problem-solving sequences
Consider the following according to the clinical question and findings:
- Thin-section oblique T2-weighted imaging or 3D T2-weighted imaging with multiplanar reformations, especially along the uterosacral ligaments
- Diffusion-weighted imaging for adnexal mass characterization
- Post-contrast T1-weighted imaging when evaluating:
- an atypical endometrioma,
- a suspected enhancing solid component,
- abdominal wall disease,
- or neural involvement
- Upper-abdominal imaging to the diaphragm when clinically indicated
Routine diaphragmatic assessment did not reach consensus; suspected thoracic or diaphragmatic disease may require a dedicated protocol.
Superficial endometriosis
Superficial endometriosis may appear as small high-signal foci on fat-suppressed T1-weighted images along a peritoneal surface.
Typical locations include:
- Ovarian fossa
- Mesosalpinx
- Pouch of Douglas
- Parietal peritoneum
What to report
- State the anatomic location.
- Measurement is optional and should be used when it adds clinical value.
- Avoid implying that MRI excludes superficial disease when no focus is visible; small superficial implants may remain occult.
Adnexal endometriosis
Micro-endometrioma
The consensus permits the term micro-endometrioma for an intraovarian, high-signal focus on fat-suppressed T1-weighted imaging measuring 1 cm or less.
Report:
- Number
- Signal characteristics
- Central or peripheral ovarian location
- Unilateral or bilateral involvement
Endometrioma
Use endometrioma for a cyst larger than 1 cm with endometriotic content and no solid tissue.
Typical MRI features include:
- High T1-weighted signal
- Low T2-weighted signal or the T2 shading sign
- A unilocular appearance in a typical lesion
Report:
- Maximum diameter
- Number of lesions
- Central or peripheral location
- Unilateral or bilateral involvement
- Residual ovarian parenchyma when relevant
- Associated hydrosalpinx or hematosalpinx
- Presence or absence of solid tissue
Solid tissue is a red flag
A suspected solid component requires careful distinction from clot. When morphology is indeterminate, absence of enhancement supports clot, whereas enhancing solid tissue requires a complete adnexal mass characterization protocol.
Consider:
- Diffusion-weighted imaging
- Dynamic contrast-enhanced MRI
- O-RADS MRI risk assessment
Enhancing solid tissue within an endometrioma raises concern for malignant or borderline transformation, including clear cell and endometrioid malignancy. The imaging finding is not itself a histologic diagnosis, but it should alter the level of concern and subsequent assessment.
Hematosalpinx
Endometriotic hematosalpinx is suggested by a dilated tubular adnexal structure containing material with high T1-weighted signal and intermediate or low T2-weighted signal.
Report:
- Content: serous, hemorrhagic, or purulent when distinguishable
- Maximum tubal caliber
- Wall thickening
- Any suspicious solid tissue, while avoiding confusion with normal tubal folds
Internal adenomyosis
Internal adenomyosis is associated with endometriosis but should be distinguished from external adenomyosis, which represents outside-in infiltration of the outer myometrium by deep endometriosis.
Direct MRI sign
- Myometrial cysts or microcysts
Indirect MRI signs
- Junctional-zone thickness greater than 11 mm
- Junctional-zone-to-myometrial thickness ratio greater than 40%
- Asymmetry of the anterior and posterior myometrium
What to report
- Present or absent
- Focal or diffuse
- Adenomyoma present or absent
Other descriptors—such as symmetric versus asymmetric, superficial versus deep, or active versus inactive—may be useful, but did not all reach the same level of consensus.
Deep endometriosis: use compartment-based mapping
The consensus recommends dividing the pelvis into central and bilateral lateral regions. In practical reporting language, this can be organized as:
- Anterocentral compartment
- Mediocentral compartment
- Posterocentral compartment
- Right lateral compartment
- Left lateral compartment
- Extra-pelvic sites
These are reporting regions rather than true fascial anatomic spaces. Their purpose is to create a reproducible search pattern and communicate disease extent clearly.
Anterocentral compartment
Bladder
Bladder endometriosis is suspected when a T2-hypointense nodule or mass involves the muscular layer, often forming an obtuse angle with the bladder wall and sometimes protruding toward the lumen.
Specify the location:
- Anterior two-thirds of the dome
- Posterior third of the dome at the vesicouterine space
- Base or trigone
Report:
- Midline, right-sided, or left-sided location
- Anteroposterior diameter
- Vesicouterine-space involvement
- Distance to the nearest ureteric orifice
Laterolateral and craniocaudal measurements may be added when useful.
Proximal round ligament
Suspect involvement when the proximal round ligament is asymmetrically thickened, fibrotic, irregular, or nodular compared with the opposite side.
Report:
- Side
- Transverse diameter
- Presence of a focal nodule
- Relationship to adjacent structures
Thickness alone is not sufficiently specific; interpret it with morphology and signal features.
Mediocentral compartment
Torus uterinus and proximal uterosacral ligaments
A uterosacral ligament measuring 3 mm or less may be considered normal. Thickness by itself, however, is not sufficiently specific for endometriosis.
Consider a uterosacral ligament abnormal when:
- A nodule is visible in at least two planes
- Spiculation is visible in at least two planes
- A high-signal T1-weighted focus is present
A finding visible in only one plane should be treated as uncertain rather than definitively positive.
Report:
- Side
- Proximal or distal involvement
- Nodule or spiculation
- Mesorectal extension when present
Posterior vaginal wall
Typical findings include T2-hypointense thickening or a nodule involving the posterior wall or fornix.
Report:
- Presence and location
- Anteroposterior dimension
- Craniocaudal dimension
- Extension to the cervix, rectovaginal space, or rectum
Pouch of Douglas
Assess for partial or complete obliteration of the rectouterine space.
Report:
- Presence or absence of obliteration
- Associated nodule
- Anteroposterior and/or craniocaudal dimensions
- Adhesions or suspended/lateralized fluid when relevant
Rectovaginal septum
Use the term rectovaginal septum only for subperitoneal or retroperitoneal lesions located below the peritoneal reflection of the pouch of Douglas.
Report:
- Length
- Thickness
- Distance to the anal verge
This terminology should not be used indiscriminately for every lesion between the uterus, vagina, and rectum.
External adenomyosis
External adenomyosis appears as ill-defined, T2-hypointense, outside-in infiltration of the outer myometrium.
Report:
- Uterine location
- Lesion size
- Depth of myometrial invasion
- Whether disease remains subserosal or approaches/reaches the junctional zone
Posterocentral compartment
Rectal and rectosigmoid endometriosis
Rectal or rectosigmoid disease typically appears as focal T2-hypointense thickening or a mass involving the anterior bowel wall.
The classic mushroom cap sign consists of a low-signal fibromuscular base capped by relatively high-signal edematous submucosa or mucosa displaced toward the bowel lumen.
What to report for every rectal or rectosigmoid lesion
- Rectal level:
- Lower rectum
- Middle rectum
- Upper rectum
- Rectosigmoid junction
- Number of nodules
- Longitudinal extent
- Distance from the inferior lesion margin to the anal verge
- Depth of bowel-wall thickening or invasion
- Transverse dimension or percentage of circumference involved
Submucosal or mucosal edema may be described when it is helpful, but it is not a substitute for the surgically relevant measurements above.
Right and left lateral compartments
Each lateral compartment can be considered in three parts.
Anterolateral: distal round ligament
Assess for asymmetric fibrotic thickening, irregularity, or a focal nodule extending toward the deep inguinal ring or inguinal canal.
Report:
- Side
- Transverse size
- Inguinal extension
- Relationship to the femoral nerve and external iliac vessels when relevant
Mediolateral: parametrium, ureter, vessels, and hypogastric plexus
The mediolateral parametrium contains the ureter, vessels including the uterine artery, and the inferior hypogastric plexus.
Report:
- Side and craniocaudal extent
- Proximal or distal parametrial involvement
- Relationship to the uterine artery
- Relationship to the inferior hypogastric plexus
- Ureteric involvement and upstream dilatation
Ureteric endometriosis
Report:
- Diameter of the proximal ureter
- Distance from the lesion to the ureterovesical junction
- Length of the involved ureter
- Hydroureter or hydronephrosis
- Degree of circumferential involvement when it can be assessed reliably
Posterolateral: distal uterosacral ligament and sacrorectal septum
Report:
- Side
- Distal uterosacral ligament involvement
- Sacrorectal septum extension
- Relationship to the pararectal space and mesorectal fascia
- Distance or extension to the iliococcygeus component of the levator ani
This region contains a substantial portion of the hypogastric plexus; precise mapping may be important for surgical risk discussion.
Nerve and muscle involvement
Endometriosis may involve somatic nerves, pelvic muscles, and adjacent vessels.
Systematically inspect the:
- Lumbosacral plexus and sacral roots
- Sciatic nerve
- Pudendal nerve
- Obturator nerve
- Femoral nerve
Also assess the:
- Piriformis
- Obturator internus
- Levator ani
When neural disease is suspected, describe the side, nerve segment, lesion extent, signal abnormality, muscle denervation changes, and relationship to adjacent vessels or foramina.
A pelvic endometriosis MRI should include a deliberate search for:
- Abdominal wall nodules
- Cesarean-scar disease
- Umbilical disease
- Sigmoid lesions
- Ileocecal junction involvement
- Appendiceal lesions
- Inguinal canal disease
The consensus did not support routine diaphragmatic assessment in every standard pelvic examination. A dedicated upper-abdominal or thoracic protocol may be required when symptoms or prior findings raise suspicion.
A practical structured reporting checklist
The following template can be adapted to local practice.
Technique and examination quality
- Patient preparation completed or limited
- Antiperistaltic agent used or not used
- Bladder filling adequate or suboptimal
- Essential T2-weighted and T1-weighted sequences completed
- Kidneys included
- Contrast or DWI performed, with indication
- Examination limitations
Uterus and adenomyosis
- Uterine position and morphology
- Internal adenomyosis: absent, focal, diffuse, or adenomyoma
- External adenomyosis: location, size, depth
Ovaries and tubes
- Ovarian position
- Endometriomas: side, number, size, signal, central/peripheral
- Solid tissue absent or present
- Residual ovarian tissue
- Hydrosalpinx or hematosalpinx
Superficial endometriosis
- Location of visible T1-fat-suppressed peritoneal foci
Deep endometriosis
- Anterocentral compartment
- Mediocentral compartment
- Posterocentral compartment
- Right lateral compartment
- Left lateral compartment
For each lesion, document size, side, organ or space involved, and surgically relevant distances.
Urinary tract
- Bladder lesion location and AP size
- Distance to ureteric orifice
- Ureteric involvement
- Hydroureter or hydronephrosis
- Kidney appearance
Bowel
- Rectal level or rectosigmoid location
- Number of nodules
- Longitudinal extent
- Distance to anal verge
- Depth and circumference
- Other bowel sites
Nerves, muscles, and extra-pelvic sites
- Neural involvement
- Pelvic sidewall muscles
- Abdominal wall and scars
- Inguinal canals
- Ileocecal region and appendix
- Diaphragm when clinically indicated
Reporting takeaway
- The minimum MRI protocol combines multiplanar T2-weighted imaging, T1-weighted imaging with fat suppression or Dixon, and a sequence that visualizes the kidneys.
- Superficial endometriosis may appear as bright peritoneal foci on fat-suppressed T1-weighted images.
- A typical endometrioma is T1-hyperintense and may demonstrate T2 shading; enhancing solid tissue requires dedicated adnexal characterization.
- A uterosacral ligament should not be called abnormal on thickness alone. A nodule or spiculation in at least two planes, or a T1-bright focus, provides stronger support.
- Deep endometriosis should be mapped systematically by compartment.
- Rectal lesions require the distance to the anal verge, longitudinal extent, depth of wall involvement, number, and location.
- Bladder lesions require precise location, anteroposterior size, and distance to the ureteric orifice.
- Ureteric, neural, muscular, and extra-pelvic disease should be actively sought rather than treated as incidental afterthoughts.